Wong-You-Cheong J, Radford J A
Department of Diagnostic Radiology, Christie Hospital NHS Trust, Manchester.
Clin Radiol. 1995 Jan;50(1):61-2. doi: 10.1016/s0009-9260(05)82969-1.
A patient with Hodgkin's Disease (HD) is described as one in whom a mediastinal mass showed progressive enlargement during the first two cycles of chemotherapy owing to accumulation of fluid within thymic cysts. This phenomenon was identified by computed tomography. Dependence on plain radiography would have led to an erroneous diagnosis of progressive HD. We suggest that in all cases of mediastinal HD, apparent failure to respond to treatment must be further investigated by computed tomography or magnetic resonance imaging. Such a policy should avoid unnecessary changes in therapy when enlargement of thymic cysts causing mediastinal widening is mistakenly interpreted as being due to progressive disease.
一名患有霍奇金淋巴瘤（HD）的患者被描述为，其纵隔肿块在化疗的前两个周期中由于胸腺囊肿内液体蓄积而逐渐增大。这种现象通过计算机断层扫描得以识别。若仅依赖胸部X光片，将会导致对进行性HD的误诊。我们建议，对于所有纵隔HD病例，若出现明显的治疗无反应情况，必须通过计算机断层扫描或磁共振成像作进一步检查。当胸腺囊肿增大导致纵隔增宽被错误地解释为是由疾病进展所致时，这样的策略应可避免不必要的治疗方案改变。
