[生长抑素受体闪烁扫描术及内镜超声检查用于胰岛素瘤和胃泌素瘤的诊断]

[Somatostatin receptor scintigraphy and endoscopic ultrasound for the diagnosis of insulinoma and gastrinoma].

作者信息

Zimmer T, Stölzel U, Liehr R M, Bäder M, Fett U, Hamm B, Wiedenmann B, Riecken E O

机构信息

Abteilung für Innere Medizin mit Schwerpunkt Gastroenterologie, Medizinische Klinik und Poliklinik, Universitätsklinikum Benjamin Franklin, Berlin.

出版信息

Dtsch Med Wochenschr. 1995 Jan 27;120(4):87-93. doi: 10.1055/s-2008-1047641.

DOI:10.1055/s-2008-1047641

PMID:7835241

Abstract

In a prospective study of 13 patients (three males and 10 females; mean age 53 [8-82] years) the value of somatostatin receptor scintigraphy (SRS) and endoscopic ultrasonography (EUS) was compared with transabdominal ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) in the diagnosis of insulinoma (six patients) or gastrinoma (seven patients). There were ten separate primary lesions of each tumour type, proven histologically. For insulinoma the sensitivity of EUS was 90%, SRS 10% and CT, US and MRI together 20%. For gastrinoma the sensitivity of EUS was 90%, SRS 100%, and 30% for the other three methods together. Thus EUS had a high diagnostic localizing sensitivity for both tumours, while SRS was highly sensitive only in the diagnosis of gastrinoma, not insulinoma. The value of CT, MRI and conventional ultrasonography lies in their ability to visualize distant metastases.

摘要

在一项针对13例患者（3例男性和10例女性；平均年龄53岁[8 - 82岁]）的前瞻性研究中，对胰岛素瘤（6例患者）或胃泌素瘤（7例患者）进行诊断时，将生长抑素受体闪烁扫描（SRS）和内镜超声检查（EUS）的值与经腹超声（US）、计算机断层扫描（CT）和磁共振成像（MRI）进行了比较。每种肿瘤类型均有10个独立的原发性病变，经组织学证实。对于胰岛素瘤，EUS的敏感性为90%，SRS为10%，CT、US和MRI三者联合为20%。对于胃泌素瘤，EUS的敏感性为90%，SRS为100%，其他三种方法联合为30%。因此，EUS对两种肿瘤均具有较高的诊断定位敏感性，而SRS仅在胃泌素瘤的诊断中高度敏感，对胰岛素瘤不敏感。CT、MRI和传统超声的价值在于它们能够显示远处转移灶。