Zenebe G
Department of Internal Medicine, Faculty of Medicine, Addis Abeba University.
Ethiop Med J. 1994 Oct;32(4):265-8.
An 18 year old male patient was admitted to the Medical Intensive Care Unit of the Tikur Anbessa Hospital in October 1988. He was in deep coma and had findings consistent with a left lobar pneumonia. Lumbar puncture revealed a turbid CSF. Gram stain on both centrifuged and uncentrifuged specimens revealed plenty of gram positive diplococci with no single inflammatory cell. CSF culture proved the organism to be Streptococcus pneumoniae. The patient was put on combination of high doses of intravenous sodium-penicillin and chloramphenicol with all appropriate supportive management. However, the patient died only after three hours of stay in the hospital. The condition of diminished to absent inflammatory response in the CSF associated with pneumococcal meningitis in adults is discussed with a review of the literature.
1988年10月，一名18岁男性患者被收治入提库尔·安贝萨医院的医学重症监护病房。他处于深度昏迷状态，检查结果符合左叶肺炎。腰椎穿刺显示脑脊液浑浊。对离心和未离心标本进行革兰氏染色，均发现大量革兰氏阳性双球菌，无单个炎症细胞。脑脊液培养证明该病原体为肺炎链球菌。患者接受了大剂量静脉注射青霉素钠和氯霉素的联合治疗以及所有适当的支持治疗。然而，患者在住院仅三小时后就死亡了。本文结合文献综述，讨论了成人肺炎球菌脑膜炎相关脑脊液中炎症反应减弱或缺失的情况。
