Long-term effects of thrombolytic therapy on clinical course and left ventricular function after acute myocardial infarction.

Sixty five cases of Acute Myocardial Infarction, of which 40 cases received thrombolytic therapy, were followed up for a period of one year for clinical course and left ventricular function. Reperfusion was achieved in 65% cases who received thrombolytic therapy. At discharge and at one year treated group fared well on Killip Scale, and ejection fraction (EF), and the overally mortality was lower. This difference was more significant in the group who achieved reperfusion. Male sex, Anterior wall infarctions, deep Q wave infarctions as also low EF at the time of discharge and late cardiac events had adverse effect on the course of infarction during follow up.