Rihs F, Gutbrod K, Gutbrod B, Steiger H J, Sturzenegger M, Mattle H P
Department of Neurology, University of Berne, Inselspital, Switzerland.
Stroke. 1995 Jan;26(1):70-3. doi: 10.1161/01.str.26.1.70.
Transcranial Doppler sonography (TCD) can assess blood flow velocity changes induced by focal brain activation. Therefore, TCD may have the potential to identify hemispheric dominance for cognitive tasks.
Using a system with two TCD probes ("stereo" TCD), we monitored simultaneously both middle cerebral arteries (MCAs) of 14 healthy right-handed volunteers while they performed cognitive tasks. The averaged blood flow velocity ratio of the two MCAs and the hemispheric blood flow velocity shift induced by the cognitive task were calculated.
In every subject, language tasks resulted in blood flow velocity shift to the left compared with visuospatial tasks. Mean MCA blood flow velocity shift to the left was 1.67%, 2.01%, and 2.31% in three language tasks. Mean blood flow velocity shift to the right was 1.67% and 2.31% in two visuospatial tasks.
Bilateral simultaneous MCA blood flow velocity monitoring and averaging during cognitive tasks can help to identify hemispheric dominance for cognitive tasks in individuals.
经颅多普勒超声（TCD）可评估局灶性脑激活引起的血流速度变化。因此，TCD可能有潜力识别认知任务中的半球优势。
我们使用一个配备两个TCD探头的系统（“立体”TCD），在14名健康右利手志愿者执行认知任务时，同时监测他们双侧的大脑中动脉（MCA）。计算了两条MCA的平均血流速度比值以及认知任务引起的半球血流速度变化。
在每个受试者中，与视觉空间任务相比，语言任务导致血流速度向左偏移。在三项语言任务中，大脑中动脉平均血流速度向左偏移分别为1.67%、2.01%和2.31%。在两项视觉空间任务中，平均血流速度向右偏移分别为1.67%和2.31%。
在认知任务期间双侧同时监测MCA血流速度并进行平均计算，有助于识别个体认知任务中的半球优势。
