Davidsen M B, Nielsen S P, Sele V
Billeddiagnostisk afdeling og gynaekologisk-obstetrisk afdeling, Hillerød Sygehus.
Ugeskr Laeger. 1994 Nov 14;156(46):6861-4.
We intended to evaluate ultrasonographic criteria for differentiation of benign and malignant ovarian tumours, and to estimate the risk of malignancy in unilocular ovarian cysts. The files of 186 women aged 40 or above, who had undergone surgery in the department of gynaecology and obstetrics at Hillerød hospital between 01.01.1988-31.12.1990 and where pathological ovarian histology was found were reviewed. Preoperative ultrasonographic examination concerning size and morphology was compared to histological diagnosis. Tumours were classified according to the ultrasonographic internal structure into a) unilocular cysts, b) unilocular cysts with solid areas, c) multilocular cysts, d) multilocular cysts with solid areas and e) solid tumours. Criteria for suspicion of malignancy were unilocular cysts > 10 cm and complex and solid tumours, whereas smaller unilocular cysts were thought to be benign. Twenty-one tumours, diagnosed by ultrasound as unilocular cysts were all histologically benign, independently of size. For complex and solid tumors there was an increased risk of malignancy, and a statistically significant correlation between tumour size and risk of malignancy was found. Using the ultrasonographic criteria for malignancy a sensitivity of 97% and a specificity of 28% was found. The suggested criteria for ultrasonographic suspicion of malignancy were found usable in differentiating benign and malignant ovarian tumours. The risk of malignancy for unilocular cysts seems to be low, independently of size.
我们旨在评估超声检查标准对卵巢良恶性肿瘤的鉴别能力，并估计单房性卵巢囊肿的恶性风险。回顾了186例40岁及以上女性的病历，这些女性于1988年1月1日至1990年12月31日在希勒勒医院妇产科接受了手术，且术后病理检查发现存在卵巢组织学病变。将术前超声检查的大小和形态与组织学诊断进行比较。根据超声检查的内部结构，将肿瘤分为：a）单房囊肿；b）有实性区域的单房囊肿；c）多房囊肿；d）有实性区域的多房囊肿；e）实性肿瘤。怀疑恶性的标准为单房囊肿直径> 10 cm以及复杂和实性肿瘤，而较小的单房囊肿被认为是良性的。超声诊断为单房囊肿的21个肿瘤经组织学检查均为良性，与大小无关。对于复杂和实性肿瘤，恶性风险增加，且发现肿瘤大小与恶性风险之间存在统计学显著相关性。使用超声恶性标准，敏感性为97%，特异性为28%。所建议的超声怀疑恶性标准可用于鉴别卵巢良恶性肿瘤。单房囊肿的恶性风险似乎较低，与大小无关。
