Khyshiktuev B S, Khyshiktueva N A, Ivanov V N, Darenskaia S D, Novikov S V
Vopr Med Khim. 1994 Sep-Oct;40(5):48-50.
The fatty acid spectrum of blood plasma and erythrocytic membrane lipids were studied in 47 patients with lung cancer. The changes in the plasma and erythrocyte fatty acid composition were found to be identical irrespective of the clinical cancer form. In blood plasma of these patients with lung cancer, a decrease in the level of polyunsaturated fatty acids was observed with the normal levels of arachidonic acid and the proportion of monoenic fatty acids was increased. Changes in the lipid composition of erythrocyte membranes were characterized by less pronounced polyunsaturated fatty acid deficiency than that in the plasma, which accompanied by decreases in arachidonic acid levels. The appearance of significant levels of nonadecanoic acid also seems striking.
