Cohen S, Amar D, Pantuck E J, Singer N, Divon M
Department of Anesthesiology, Albert Einstein College of Medicine, Bronx, NY.
Acta Anaesthesiol Scand. 1994 Oct;38(7):716-8. doi: 10.1111/j.1399-6576.1994.tb03983.x.
To examine the effects of prolonged (> 24 h) intrathecal catheterization with the use of postoperative analgesia on the incidence of post-dural puncture headache (PDPH), charts of 45 obstetric patients who had accidental dural puncture following attempts at epidural block were reviewed retrospectively. Three groups were identified: Group I (n = 15) patients had a dural puncture on the first attempt at epidural block, but successful epidural block on a repeated attempt; Group II (n = 17) patients had a dural puncture with immediate conversion to continuous spinal anaesthesia with catheterization lasting only for the duration of caesarean delivery; Group III (n = 13) patients had an immediate conversion to spinal anaesthesia and received post-caesarean section continuous intrathecal patient-controlled analgesia consisting of fentanyl 5 micrograms.ml-1 with bupivacaine 0.25 mg.ml-1 and epinephrine 2 micrograms.ml-1 with catheterization lasting > 24 h. No parturient in group III developed a PDPH. This was substantially lower (P < 0.009) than the 33% incidence for group I and the 47% incidence for group II. The incidence of a PDPH did not differ between group I and II. Similarly, there was no difference between group I and II with regard to requests for a blood patch. Patients receiving continuous intrathecal analgesia had excellent pain relief, could easily ambulate and none complained of pruritus, nausea, vomiting, sensory loss or weakness. In conclusion, indwelling spinal catheterization > 24 h with continuous intrathecal analgesia following accidental dural puncture in parturients may for some patients be a suitable method for providing PDPH prophylaxis and postoperative analgesia.
为研究术后镇痛时延长鞘内导管置入时间(>24小时)对硬膜穿刺后头痛(PDPH)发生率的影响,我们回顾性分析了45例硬膜外阻滞穿刺时意外穿破硬膜的产科患者的病历。分为三组:第一组(n = 15)患者在首次硬膜外阻滞穿刺时穿破硬膜,但再次穿刺成功;第二组(n = 17)患者穿刺破膜后立即改为持续脊髓麻醉,导管仅在剖宫产期间留置;第三组(n = 13)患者立即改为脊髓麻醉,并在剖宫产术后接受持续鞘内患者自控镇痛,药物为5微克/毫升芬太尼、0.25毫克/毫升布比卡因和2微克/毫升肾上腺素,导管留置时间>24小时。第三组无产妇发生PDPH。这一发生率显著低于第一组的33%和第二组的47%(P < 0.009)。第一组和第二组的PDPH发生率无差异。同样,第一组和第二组在血液补片需求方面也无差异。接受持续鞘内镇痛的患者疼痛缓解良好,可轻松活动,且均无瘙痒、恶心、呕吐、感觉丧失或无力的主诉。总之,对于部分产妇,硬膜穿刺意外后留置鞘内导管>24小时并持续鞘内镇痛可能是预防PDPH和提供术后镇痛的合适方法。