Keidan I, Lotan D, Gazit G, Boichis H, Reichman B, Linder N
Pediatric Renal Unit, Chaim Sheba Medical Center, Sackler School of Medicine, Tel Aviv, Israel.
Acta Paediatr. 1994 Nov;83(11):1225-7. doi: 10.1111/j.1651-2227.1994.tb18291.x.
Renal venous thrombosis was diagnosed in the first week of life in 6 of 30,101 live infant births born at the Chaim Sheba Medical Center in Israel from 1984 to 1989. The thrombosis was unilateral in 5 neonates and bilateral in 1. Predisposing maternal risk factors included 2 cases of maternal diabetes and 1 case of maternal hypertension with associated intrauterine growth retardation. Perinatal risk factors included 2 cases of prematurity with severe hyaline membrane disease, 1 infant who was small for gestational age and another with asphyxia. Follow-up for 1-5 years following the acute event revealed normal growth and development in all infants. None of the patients was hypertensive and all had normal renal glomerular and tubular functions. Renal imaging and scan studies revealed loss of perfusion in 4 atrophic kidneys and diminished perfusion in the remaining 2. In conclusion, although renal venous thrombosis in neonates is associated with low mortality, long-term dysfunction in the affected kidney is common.
1984年至1989年在以色列海姆·谢巴医疗中心出生的30101例活产婴儿中，有6例在出生后第一周被诊断为肾静脉血栓形成。5例新生儿血栓形成是单侧的，1例是双侧的。母亲的易感危险因素包括2例母亲患有糖尿病和1例母亲患有高血压并伴有宫内生长迟缓。围产期危险因素包括2例早产并患有严重透明膜病、1例小于胎龄儿和另1例窒息儿。急性事件发生后1至5年的随访显示，所有婴儿生长发育正常。所有患者均无高血压，肾小球和肾小管功能均正常。肾脏成像和扫描研究显示，4个萎缩肾灌注丧失，其余2个灌注减少。总之，尽管新生儿肾静脉血栓形成死亡率较低，但受影响肾脏的长期功能障碍很常见。
