Qiu M C, Li Y K, Liu W B
Affiliated Hospital, Tianjin Medical College, Tianjin.
Zhonghua Yi Xue Za Zhi. 1994 Sep;74(9):527-9, 581.
By bone histomorphometry, 10 cases of primary hyperparathyroidism (PHPT) were used to study the trabecular connectivity, which in a few literatures was mentioned to be reserved somehow. Our data suggest that in comparison with the normal control (10 subjects) the nodes (N.Nd), the number of terminus (N.Tm), the total strut length (TSL), the length between the nodes (Nd.Nd), trabecular separation (Tb.Sp) and trabecular thickness (Tb.Th) were significantly increased while no significance was found in N.Nd/N.Tm, Tm.Tm and TBV. The correlation analyses indicate that there is no correlation between the variables in the normal controls. In contrast, however, TBV and Tb.Th showed negative correlations with N.Tm and Tm.Tm. Besides these, there were positive correlations between N.Nd/N.Tm and TBV or Tb.Th, and a negative correlation between N.Nd/N.Tm and Tb.Sp. The results suggest that to certain degree the trabecular connectivity in PHPT be destructed while the three dimensional architecture be reserved. Our data seem to be different from those reported previously. It may be due to the severity of PHPT in our patients.
通过骨组织形态计量学,对10例原发性甲状旁腺功能亢进症(PHPT)患者进行小梁连接性研究,小梁连接性在一些文献中曾被提及在一定程度上得以保留。我们的数据表明,与正常对照组(10名受试者)相比,节点数(N.Nd)、终点数(N.Tm)、骨小梁总长度(TSL)、节点间长度(Nd.Nd)、骨小梁间距(Tb.Sp)和骨小梁厚度(Tb.Th)显著增加,而N.Nd/N.Tm、Tm.Tm和骨小梁体积(TBV)无显著差异。相关性分析表明,正常对照组各变量之间无相关性。然而,相比之下,TBV和Tb.Th与N.Tm和Tm.Tm呈负相关。此外,N.Nd/N.Tm与TBV或Tb.Th呈正相关,与Tb.Sp呈负相关。结果表明,PHPT患者的小梁连接性在一定程度上遭到破坏,而三维结构得以保留。我们的数据似乎与先前报道的不同。这可能是由于我们研究中患者PHPT的严重程度所致。