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3个候选肿瘤抑制基因相对于11p15.3处贝克威思-维德曼综合征相关染色体断点的物理图谱。

Physical mapping of 3 candidate tumor suppressor genes relative to Beckwith-Wiedemann syndrome associated chromosomal breakpoints at 11p15.3.

作者信息

Redeker E, Alders M, Hoovers J M, Richard C W, Westerveld A, Mannens M

机构信息

Institute of Human Genetics, University of Amsterdam, The Netherlands.

出版信息

Cytogenet Cell Genet. 1995;68(3-4):222-5. doi: 10.1159/000133917.

DOI:10.1159/000133917
PMID:7842740
Abstract

A physical map encompassing the 3 Mb region containing the breakpoints of two Beckwith-Wiedemann Syndrome patients at chromosome band 11p15.3 is presented. The candidate tumor suppressor genes WEE1, ST5, and rhombotin, are positioned on this map relative to these Beckwith-Wiedemann syndrome translocation and inversion breakpoints.

摘要

本文展示了一个物理图谱，该图谱涵盖了位于11号染色体15.3带区、包含两名贝克威思-维德曼综合征患者断点的3 Mb区域。候选肿瘤抑制基因WEE1、ST5和菱蛋白，相对于这些贝克威思-维德曼综合征易位和倒位断点，定位在该图谱上。

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