与CD3Z基因重叠的人类OTF1基因座位于1q22→q23。
The human OTF1 locus which overlaps the CD3Z gene is located at 1q22-->q23.
作者信息
Sturm R A, Eyre H J, Baker E, Sutherland G R
机构信息
Centre for Molecular Biology and Biotechnology, University of Queensland, Brisbane, Australia.
出版信息
Cytogenet Cell Genet. 1995;68(3-4):231-2. doi: 10.1159/000133919.
PMID:7842742
Abstract
The human OTF1 locus encoding the Oct-1 protein has previously been mapped to chromosome 1 cen-->q32 by analysis of somatic cell hybrids. We report here the regional localization of OTF1 to 1q22-->q23 by fluorescence in situ hybridization. The physical linkage of the CD3Z gene to the OTF1 transcription unit also refines the location of the CD3Z locus to 1q22-->q23.
摘要
通过对体细胞杂种的分析，先前已将编码Oct-1蛋白的人类OTF1基因座定位于1号染色体着丝粒→q32。我们在此报告通过荧光原位杂交将OTF1区域定位到1q22→q23。CD3Z基因与OTF1转录单位的物理连锁也将CD3Z基因座的位置精确到1q22→q23。
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