Sutedja T G, Schreurs A J, Vanderschueren R G, Kwa B, vd Werf T S, Postmus P E
Department of Pulmonary Medicine, Free University Hospital Amsterdam, The Netherlands.
Chest. 1995 Feb;107(2):556-8. doi: 10.1378/chest.107.2.556.
To study the efficacy of bronchoscopic therapy in patients with intraluminal typical bronchial carcinoid.
Retrospective analysis of the data of patients with bronchial carcinoid, treated primarily with bronchoscopic techniques such as Nd-YAG laser in various hospitals in the Netherlands.
Eleven patients with pulmonary complaints, ages 22 to 60 years, who were found to have intraluminal typical bronchial carcinoid. BRONCHOSCOPIC INTERVENTIONS: Six of the 11 patients received Nd-YAG laser treatments, one received Nd-YAG laser plus photodynamic therapy, and the other four had mechanical tumor removal.
Six patients were surgically treated after bronchoscopic therapy. The resected specimens showed no residual carcinoid. Median follow-up has been 70 months (range, 9 to 170 months). Five patients were not surgically treated after bronchoscopic therapy. Follow-up has been 27 to 246 months (median, 47 months) without signs of recurrence.
In 11 patients with typical, intraluminal, bronchial carcinoids, bronchoscopic treatment seemed to result in excellent local control, with surgical proof of cure in 6 of 11 patients. Bronchoscopic approach may provide a tissue-sparing alternative for bronchoplastic surgery in a subset of patients with typical intraluminal bronchial carcinoids.
研究支气管镜治疗腔内典型支气管类癌患者的疗效。
对荷兰多家医院主要采用如Nd-YAG激光等支气管镜技术治疗的支气管类癌患者的数据进行回顾性分析。
11例有肺部症状、年龄在22至60岁之间、被发现患有腔内典型支气管类癌的患者。
11例患者中，6例接受了Nd-YAG激光治疗，1例接受了Nd-YAG激光加光动力疗法，另外4例进行了肿瘤机械切除。
6例患者在支气管镜治疗后接受了手术治疗。切除标本显示无类癌残留。中位随访时间为70个月（范围9至170个月）。5例患者在支气管镜治疗后未接受手术治疗。随访时间为27至246个月（中位时间47个月），无复发迹象。
在11例典型的腔内支气管类癌患者中，支气管镜治疗似乎能实现良好的局部控制，11例中有6例经手术证实治愈。对于部分典型腔内支气管类癌患者，支气管镜治疗方法可为支气管成形手术提供一种保留组织的替代方案。
