Huan J N, Chen Y L, Ge S D
Burn Institute, Changhai Hospital, Shanghai.
Zhonghua Wai Ke Za Zhi. 1994 Apr;32(4):244-5.
Burn wound and systemic infections caused by methicillin-resistant Staphylococcus aureus (MRSA) were analysed in 95 patients. Results showed that both 95 (92.2%) out of 103 strains of Staphylococcus aureus isolated from burn wound and all 17 strains from blood were MRSA. Wound MRSA infection could be found in patients with variety of severity and in any kind of wound, while systemic MRSA infection was often occurred in extensive burn patients. The isolated MRSA were most resistant to cephalosporins and sensitive to vancomycin. In order to control wound MRSA infection, Lysostaphin which is active against these organisms could be used as a topical antimicrobial.
对95例耐甲氧西林金黄色葡萄球菌（MRSA）引起的烧伤创面感染和全身感染进行了分析。结果显示，从烧伤创面分离出的103株金黄色葡萄球菌中有95株（92.2%）以及从血液中分离出的所有17株均为MRSA。不同严重程度的患者以及任何类型的创面均可发生创面MRSA感染，而全身MRSA感染常发生于大面积烧伤患者。分离出的MRSA对头孢菌素耐药性最强，对万古霉素敏感。为控制创面MRSA感染，可使用对这些微生物有活性的溶葡萄球菌酶作为局部抗菌药物。
