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老年初级保健就诊者抑郁症的筛查、检测与管理。I:15项老年抑郁量表(GDS15)的可接受性与性能及简版的开发

Screening, detection and management of depression in elderly primary care attenders. I: The acceptability and performance of the 15 item Geriatric Depression Scale (GDS15) and the development of short versions.

作者信息

D'Ath P, Katona P, Mullan E, Evans S, Katona C

机构信息

Princess Alexandra Hospital, Harlow, Essex, UK.

出版信息

Fam Pract. 1994 Sep;11(3):260-6. doi: 10.1093/fampra/11.3.260.

DOI:10.1093/fampra/11.3.260
PMID:7843514
Abstract

One-hundred and ninety-eight elderly subjects attending their general practitioners (GPs) were asked to complete the 15 item Geriatric Depression Scale (GDS15). Analysable results were obtained from 194 (98%). Of these, 67 (34%) scored above the GDS15 cut-off (4/5) for significant depressive symptomatology. 87.6% found the questionnaire to be acceptable and only 3.6% found it very difficult or very stressful. The GDS15 had a high level of internal consistency (Cronbach's alpha = 0.80). All the individual items of the GDS15 associated significantly (P < 0.01) with total score and 'caseness'. A single question "do you feel that your life is empty?" identified 84% of 'cases'. In an attempt to devise short scales to screen elderly primary care patients for depression, the data were subjected to logistic regression analysis. Ten (GDS10), four (GDS4) and on (GDS1) item versions were generated. Agreement between these short scales and the GDS15 in the original sample was 95, 91 and 79% respectively. Cronbach's alpha was 0.72 for the GDS10 and 0.55 for the GDS4. The short scales were then validated in an independent sample of 120 patients in whom both GDS data and the results of a detailed psychiatric interview (the Geriatric Mental Status Schedule, GMS) were available. The sensitivity and specificity of the GDS10 against GMS caseness were 87 and 77% (cut-off 3/4); those of the GDS4 were 89 and 65% (cut-off 0/1) and 61 and 81% (cut-off 1/2). Sensitivity and specificity for the GDS1 were 59 and 75%. It is concluded that these short scales may be useful in helping GPs and practice staff to identify elderly patients with significant depressive symptoms.

摘要

198名到全科医生(GP)处就诊的老年受试者被要求完成15项老年抑郁量表(GDS15)。194名(98%)获得了可分析的结果。其中,67名(34%)的得分高于GDS15的临界值(4/5),表明有明显的抑郁症状。87.6%的人认为该问卷可以接受,只有3.6%的人觉得非常困难或压力很大。GDS15具有较高的内部一致性(克朗巴哈系数α=0.80)。GDS15的所有单项与总分及“病例状态”均有显著相关性(P<0.01)。一个单一问题“你是否觉得你的生活很空虚?”识别出了84%的“病例”。为了设计简短量表以筛查老年初级保健患者的抑郁症,对数据进行了逻辑回归分析。生成了10项(GDS10)、4项(GDS4)和1项(GDS1)版本的量表。在原始样本中,这些简短量表与GDS15的一致性分别为95%、91%和79%。GDS10的克朗巴哈系数α为0.72,GDS4的为0.55。然后,在一个由120名患者组成的独立样本中对这些简短量表进行验证,这些患者既有GDS数据,又有详细的精神科访谈结果(老年精神状态检查表,GMS)。GDS10相对于GMS病例状态的敏感性和特异性分别为87%和77%(临界值3/4);GDS4的敏感性和特异性分别为89%和65%(临界值0/1)以及61%和81%(临界值1/2)。GDS1的敏感性和特异性分别为59%和75%。结论是,这些简短量表可能有助于全科医生和医疗机构工作人员识别有明显抑郁症状的老年患者。

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