Stuppy W P, Shipko S
Int J Psychosom. 1994;41(1-4):30-3.
This manuscript presents a novel model of psychophysiologic markers for the stress response. The hypothesis describes what we believe is a human analogue of the physiologic changes described in animal models of inescapable shock. This is bolstered by laboratory and clinical data derived from patients with stress-related functional gastrointestinal disorders. The idea explains the clinical findings of simultaneous analgesia and somatization in alexithymics. The implications for understanding the physiologic relationship between panic disorder and functional bowel disorders in the context of the stress response is discussed along with novel treatment strategies for these disabling conditions.
本手稿提出了一种应激反应心理生理标志物的新模型。该假设描述了我们认为是与无法逃避的休克动物模型中所描述的生理变化类似的人类情况。来自与应激相关的功能性胃肠疾病患者的实验室和临床数据支持了这一点。该观点解释了述情障碍患者同时存在镇痛和躯体化的临床发现。本文讨论了在应激反应背景下理解惊恐障碍与功能性肠病之间生理关系的意义，以及针对这些致残性疾病的新治疗策略。
