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原发性抗磷脂综合征(PAPS)与青少年孤立性部分性癫痫:一例报告

Primary antiphospholipid syndrome (PAPS) and isolated partial seizures in adolescence. A case report.

作者信息

Spreafico R, Binelli S, Bruzzone M G, Croci D, Rumi V, Angelini L

机构信息

Divisione Neurofisiologia, Istituto Nazionale Neurologico C. Besta, Milano.

出版信息

Ital J Neurol Sci. 1994 Sep;15(6):297-301. doi: 10.1007/BF02339240.

DOI:10.1007/BF02339240
PMID:7843945
Abstract

The case of a young male patient presenting isolated clustered partial seizures is reported. Despite the normality of the neurological features, as well as of ictal and interictal EEG, the MRI (performed three days after the symptoms) disclosed bilateral signal alterations in the parietal cortical region. These abnormalities disappeared at the MRI control examination performed one month later. The finding of positive anticardiolipine antibodies made possible the diagnosis of partial epileptic seizures symptomatic of a vascular disorder ascribed to a Primary antiphospholipid Syndrome (PAPS).

摘要

报告了一例表现为孤立性丛集性部分性癫痫发作的年轻男性患者。尽管神经学特征以及发作期和发作间期脑电图均正常,但(症状出现三天后进行的)MRI显示顶叶皮质区域双侧信号改变。这些异常在一个月后进行的MRI对照检查中消失。抗心磷脂抗体阳性的发现使得诊断为原发性抗磷脂综合征(PAPS)所致血管疾病症状性部分性癫痫发作成为可能。

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