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[鼻腔坏死性涎腺化生]

[Necrotizing sialometaplasia of the nasal cavity].

作者信息

Deubel M, Meister F, Podvinec M, Stamm B

机构信息

HNO-Klinik, Kantonsspital Aarau.

出版信息

HNO. 1994 Nov;42(11):697-700.

PMID:7844002
Abstract

In the present paper we report two cases of "necrotizing sialometaplasia" in uncommon locations. The relevant literature is reviewed. Necrotizing sialometaplasia is self-limiting and is characterized by necrosis and squamous pseudohypertrophy. Typically occurring in the minor salivary glands of the oral mucosa, our cases appear to be the sixth and seventh cases of involvement of the nasal cavity reported in the literature. Owing to the similarity of histological findings, the term "sialometaplasia" is also used for this disorder. This rare disease is a benign process but may be misdiagnosed as mucoepidermoid or squamous cell carcinoma. Therefore, the possibility of this disease in the nose should again be presented. Both of our cases show that with a histological examination considering defined morphological findings, the diagnosis of necrotizing sialometaplasia can be verified and a diagnosis of a carcinoma can be excluded. Especially with regard to radical and possibly unnecessary invasive therapeutic procedures we emphasize the importance of considering "necrotizing sialometaplasia" as part of the differential diagnosis of nasal lesions.

摘要

在本文中,我们报告了两例发生于不常见部位的“坏死性涎腺化生”病例。并对相关文献进行了综述。坏死性涎腺化生具有自限性,其特征为坏死和鳞状上皮假肥大。该病通常发生于口腔黏膜的小涎腺,而我们的病例似乎是文献报道的第六和第七例累及鼻腔的病例。由于组织学表现相似,“涎腺化生”这一术语也用于描述该疾病。这种罕见疾病是一种良性病变,但可能被误诊为黏液表皮样癌或鳞状细胞癌。因此,有必要再次提及鼻腔发生这种疾病的可能性。我们的两个病例均表明,通过组织学检查并结合明确的形态学表现,可以确诊坏死性涎腺化生并排除癌的诊断。特别是在考虑根治性且可能不必要的侵入性治疗程序时,我们强调将“坏死性涎腺化生”作为鼻腔病变鉴别诊断的一部分的重要性。

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