Goldenberg J N, Brown S B, Weiner W J
Department of Neurology, University of Miami School of Medicine, Florida 33136.
Mov Disord. 1994 Nov;9(6):622-5. doi: 10.1002/mds.870090607.
The objective of this study was to determine the frequency of coprolalia in younger patients with Gilles de la Tourette syndrome (GTS). Coprolalia, which is the least understood and perhaps most unusual symptom of GTS, is reported to occur in 4-60% of all patients with GTS. Most reports indicate a prevalence > 30%. The widely varying prevalence figures for coprolalia may reflect cultural differences, severity of disease, and the age of the population surveyed. This study is a chart review of 112 patients seen in a pediatric neurology clinic in South Florida who met the Diagnostic and Statistical Manual of Mental Disorder (3rd ed., revised) criteria for GTS. Only 8% of the patients in the study exhibited coprolalia. This unusually low frequency of coprolalia suggests that coprolalia may be rarer than previously believed in younger patients. It may also better reflect the frequency of coprolalia in a community-based pediatric neurology practice.
本研究的目的是确定较年轻的抽动秽语综合征(GTS)患者中秽语症的发生率。秽语症是GTS中最不为人所理解且可能最为特殊的症状,据报道在所有GTS患者中的发生率为4% - 60%。大多数报告表明患病率>30%。秽语症患病率的广泛差异可能反映了文化差异、疾病严重程度以及所调查人群的年龄。本研究是对在南佛罗里达一家儿科神经科诊所就诊的112例符合《精神障碍诊断与统计手册》(第3版,修订版)GTS标准的患者进行的病历回顾。该研究中只有8%的患者表现出秽语症。秽语症这种异常低的发生率表明,在较年轻的患者中,秽语症可能比之前认为的更为罕见。它也可能更好地反映了社区儿科神经科实践中秽语症的发生率。