Lebert F, Pasquier F, Steinling M, Cabaret M, Caparros-Lefebvre D, Petit H
Memory Disorders, Unit, Hospitalier Régional, Universitaire, Lille, France.
Psychopathology. 1994;27(3-5):211-4. doi: 10.1159/000284871.
Capgras' delusion (CD) may be secondary to a neurologic lesion, particularly in the right frontal or occipital regions. A 40-year-old woman with multiple sclerosis underwent SPECT during and after an episode of CD. Analysis during delusion showed an uptake defect in the right parietal cortex with an 11% index of asymmetry (normal: < or = 4%). Post-delusion SPECT showed decreased bifrontal and biparietal cortical uptake indices but a normal index of asymmetry. Functional brain imaging may provide clues to the psychopathology of CD.
卡普格拉妄想症(CD)可能继发于神经病变,尤其是右侧额叶或枕叶区域的病变。一名患有多发性硬化症的40岁女性在一次卡普格拉妄想症发作期间及之后接受了单光子发射计算机断层扫描(SPECT)。妄想发作期间的分析显示右侧顶叶皮质有摄取缺陷,不对称指数为11%(正常:≤4%)。妄想发作后的SPECT显示双侧额叶和双侧顶叶皮质摄取指数降低,但不对称指数正常。功能性脑成像可能为卡普格拉妄想症的精神病理学提供线索。