癌症发生的生物学模型与定量癌症风险评估
Biological models of carcinogenesis and quantitative cancer risk assessment.
作者信息
Moolgavkar S H
出版信息
Risk Anal. 1994 Dec;14(6):879-82. doi: 10.1111/j.1539-6924.1994.tb00049.x.
Abstract
Biologically-based models of carcinogenesis were originally developed to explain certain quantitative phenomena associated with carcinogenesis, and to provide a framework within which questions regarding the process could be addressed. Some limitations in the use of these models for quantitative cancer risk assessment are discussed.
摘要
基于生物学的致癌模型最初是为了解释与致癌作用相关的某些定量现象，并提供一个能够探讨该过程相关问题的框架而开发的。本文讨论了这些模型在用于定量癌症风险评估时的一些局限性。
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