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[包涵体肌炎:3例家族性报告]

[Inclusion-body myositis: a familial report of 3 cases].

作者信息

Miró i Andreu O, Fernández-Solá J, Pedrol Clotet E, Coll-Vinent B, Casademont Pou J, Grau Junyent J M, Urbano-Márquez A

机构信息

Servicio de Medicina Interna General, Hospital Clínic i Provincial, Barcelona.

出版信息

Rev Clin Esp. 1994 Nov;194(11):974-7.

PMID:7846355
Abstract

Inclusion body myositis (IBM) is a myopathy classified until now within the group of idiopathic inflammatory myopathies (IIM). Nevertheless, its clinical and histological features are specific and different from the other IIM. It is refractory to corticosteroid therapy. Recently, a few cases of IBM with familial transmission have been described, which is the first report in our country; previous reported cases in literature are reviewed. The similarities of some forms of IBM with muscle dystrophies, rather than with inflammatory myopathies are discussed.

摘要

包涵体肌炎(IBM)是一种迄今为止归类于特发性炎症性肌病(IIM)组的肌病。然而,其临床和组织学特征具有特异性,与其他IIM不同。它对皮质类固醇治疗无效。最近,国内首次报道了几例家族性传播的IBM病例;对文献中先前报道的病例进行了综述。讨论了某些形式的IBM与肌肉营养不良而非炎症性肌病的相似之处。

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