Cosgrove G R, Steiner L
Department of Neurological Surgery, University of Virginia School of Medicine, Charlottesville.
Stereotact Funct Neurosurg. 1993;61(4):182-94. doi: 10.1159/000100636.
We describe our experience with stereotactic microsurgical resection of 27 lesions using the Leksell frame in 23 patients; 7 had cerebral metastases, 6 had gliomas, 6 had vascular malformations, 3 had meningiomas and 1 had radiation necrosis. Gross total removal of the lesion was accomplished in every case. All lesions were between 1.0 and 3.5 cm in greatest diameter and located either deep within the cerebral (n = 7) or superficially in areas of functional cortex (n = 20). There was no operative mortality and only minimal morbidity. Average length of operating time including frame application, imaging and resection was 4.4 h and most patients were discharged on the second postoperative day. The indications, advantages and limitations of stereotactic craniotomy are discussed and technical modifications that extend the usefulness and safety of this technique are described.
我们描述了使用Leksell框架对23例患者的27个病变进行立体定向显微手术切除的经验；其中7例为脑转移瘤，6例为神经胶质瘤，6例为血管畸形，3例为脑膜瘤，1例为放射性坏死。所有病例均实现了病变的全切除。所有病变最大直径在1.0至3.5厘米之间，位于脑深部（n = 7）或功能皮质表面区域（n = 20）。无手术死亡病例，发病率极低。包括安装框架、成像和切除在内的平均手术时间为4.4小时，大多数患者术后第二天出院。讨论了立体定向开颅手术的适应证、优点和局限性，并描述了扩展该技术实用性和安全性的技术改进。
