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面对高催乳素血症时该怎么做?

[What to do when faced with hyperprolactinemia?].

作者信息

Kuntschen F

机构信息

FMH en endocrinologie, Monthey.

出版信息

Praxis (Bern 1994). 1995 Jan 24;84(4):93-7.

PMID:7846438
Abstract

Hyperprolactinemia causes a certain number of clinical syndromes whose sequels vary much depending on the age group. It is a common affection as frequent in women as in males and it necessitates prolonged treatment. It may have several causes, the most frequent ones are: adverse drug reactions, prolactinomas, disturbed distribution of dopamine and hyperthyroidism. Evaluation includes repeated measurements of prolactin, T4, and TSH, a radiologic work-up including a CT-scan or magnetic resonance imaging. In the case of a prolactinoma the choice of treatment depends on size and evolution of the adenoma. Bromocriptine permits to correct hyperprolactinemia in the majority of cases. After adequate treatment of pituitary adenoma these are no contraindications for pregnancy, once fertility has returned.

摘要

高催乳素血症会引发一定数量的临床综合征,其后果因年龄组而异。这是一种常见病症,在女性和男性中发病率相当,且需要长期治疗。它可能有多种病因,最常见的是:药物不良反应、催乳素瘤、多巴胺分布紊乱和甲状腺功能亢进。评估包括多次测量催乳素、T4和TSH,以及包括CT扫描或磁共振成像在内的影像学检查。对于催乳素瘤,治疗方法的选择取决于腺瘤的大小和发展情况。在大多数情况下,溴隐亭可纠正高催乳素血症。垂体腺瘤经过适当治疗后,一旦恢复生育能力,怀孕并无禁忌。

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