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[注射鸡视网膜mRNA后在两栖类卵母细胞中表达的甘氨酸受体、乙酰胆碱受体及离子通道的研究]

[Studies on glycine receptor, acetylcholine receptor and ion channels expressed in amphibian oocytes after injection of chicken retina mRNA].

作者信息

Zhu X, Zhu H, Bao Y D

机构信息

Shanghai Institute of Physiology, Chinese Academy of Sciences.

出版信息

Sheng Li Xue Bao. 1994 Oct;46(5):495-9.

PMID:7846550
Abstract

Glycine receptor, acetylcholine receptor and voltage dependent ion channels expressed in amphibian oocytes after injection of chicken retinal mRNA were studied by using voltage clamp technique. The current response to glycine was proved as small, and the acetylcholine receptor was identified as N type. Aspartate, serotonin and dopamine induced no responses. In addition, voltage dependent ion channels were detected, and were identified as delayed rectifier potassium channel and sodium channel.

摘要

通过电压钳技术研究了注射鸡视网膜mRNA后在两栖类卵母细胞中表达的甘氨酸受体、乙酰胆碱受体和电压依赖性离子通道。证明对甘氨酸的电流反应较小,且乙酰胆碱受体被鉴定为N型。天冬氨酸、5-羟色胺和多巴胺未引起反应。此外,检测到电压依赖性离子通道,并鉴定为延迟整流钾通道和钠通道。

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