Schlemminger R, Köhler H, Lepsien G, Peiper H J
Chirurgische Klinik und Poliklinik, Georg-August-Universität Göttingen.
Zentralbl Chir. 1994;119(11):798-802; discussion 803-4.
Over the time period from July 01, 1983 to June 01, 1993, 15 patients with portal hypertension and relapsing bleedings from esophageal varicosis were treated with Chang's mesocaval side-to-side shunt at the Department of General Surgery, University Hospital of Göttingen. All patients were pre-operated in the upper abdomen or exhibited thrombosis of the portal vein. While five cases revealed a prehepatic block, ten patients had an intrahepatic block, based on cirrhosis of the liver (Child classification A or B). The time required for operations was 180 +/- 32 minutes; the pressure in the portal circulation decreased by 56%. In three cases, patients suffered relapsing bleedings despite of regular shunt conditions. Complications which were due to the procedure were seen in two patients (one revealed intraabdominal posthemorrhage, followed by therapy-resistant coagulopathy; the other patient exhibited stenosis of the anastomosis). One patient developed encephalopathy. Given a rigid indication, we regard the procedure described herein an alternative to the mesocaval interposition shunt, and we consider the low rate of thrombosis (so far < 10%) without continued postoperative anticoagulant therapy as well as the avoidance of an interposition as important advantages of this technique.
在1983年7月1日至1993年6月1日期间,哥廷根大学医院普通外科对15例门静脉高压症且食管静脉曲张反复出血的患者施行了张氏肠系膜上腔静脉侧侧分流术。所有患者均在上腹部进行过手术或存在门静脉血栓形成。其中5例为肝前性梗阻,10例因肝硬化(Child分级A或B级)存在肝内梗阻。手术所需时间为180±32分钟;门静脉循环压力下降了56%。3例患者尽管分流情况正常仍反复出血。该手术导致的并发症见于2例患者(1例出现腹腔内出血,继而发生难治性凝血病;另1例患者吻合口狭窄)。1例患者发生了脑病。在严格掌握适应证的情况下,我们认为本文所述手术可作为肠系膜上腔静脉间置分流术的替代方法,并且我们将术后无需持续抗凝治疗情况下较低的血栓形成率(目前<10%)以及避免间置视为该技术的重要优势。