Kronfeld D S
Virginia Tech, Blacksburg 24061-0306.
Aust Vet J. 1994 Oct;71(10):328-31. doi: 10.1111/j.1751-0813.1994.tb00909.x.
The need for dietary management of renal senescence and the beginning of chronic renal failure should be evaluated in all middle-aged dogs. One survey found that 35% were overweight and 10% underweight; another that 25% were mildly azotaemic, with 5% showing slight clinical signs of chronic renal failure. Dogs in prime condition or overweight are candidates for a diet low in energy (for example 3.0-3.3 kcal/g dry matter, DM), but thin dogs need a higher caloric density (such as 4.0-4.5 kcal/g DM). Healthy older dogs need higher dietary protein than the minimum for maintenance (about 20% on a metabolisable energy basis, ME) of young mature dogs. Thin older dogs showing signs of renal insufficiency may benefit from moderate protein and near-minimal phosphorus in the diet. In dogs with chronic renal failure, clinical, haematological and biochemical responses to the combination of low protein (13-16% ME) and low phosphorus (0.4% DM) were positive in one clinical trial but not in three others. Only beneficial responses, such as less proteinuria, less renal impairment and lower mortality, have been reported for diets containing low phosphorus and moderate protein (20-31% ME). Individual dietary goals for energy, protein and phosphorus should be chosen for each middle-aged or older dog; these goals may be met by a single product or mixtures of products.
应对所有中年犬评估对肾脏衰老及慢性肾衰竭初期进行饮食管理的必要性。一项调查发现,35%的犬超重,10%的犬体重过轻;另一项调查发现,25%的犬轻度氮血症,5%有慢性肾衰竭的轻微临床症状。身体状况良好或超重的犬适合食用低能量日粮(例如3.0 - 3.3千卡/克干物质,DM),但瘦犬需要更高的能量密度(如4.0 - 4.5千卡/克DM)。健康的老年犬所需的日粮蛋白质高于年轻成年犬维持需要的最低量(以代谢能为基础约20%,ME)。出现肾功能不全迹象的瘦老年犬可能会从日粮中适量的蛋白质和接近最低量的磷中受益。在一项临床试验中,低蛋白(13 - 16% ME)和低磷(0.4% DM)联合使用对患有慢性肾衰竭的犬的临床、血液学和生化反应呈阳性,但在其他三项试验中并非如此。据报道,只有含低磷和适量蛋白质(20 - 31% ME)的日粮才有诸如蛋白尿减少、肾功能损害减轻和死亡率降低等有益反应。应为每只中年或老年犬制定能量、蛋白质和磷的个体饮食目标;这些目标可以通过单一产品或产品混合物来实现。