Vayssairat M, Fiessinger J N, Bordet F, Housset E
Nouv Presse Med. 1978 Apr 15;7(15):1279-82.
The authors report six new cases of necrosis of the fingers occurring during the course of a malignant condition. None of the patient was suffering from any other disease which could explain the digital necrosis. They discuss the mechanism of the relationship between the two conditions : blood hyperviscosity, thrombocytosis, polycythaemia, cryoglobulin and the production of immune complexes. The particular role of bleomycin is mentioned. The possibility of a true paraneoplastic syndrome is suggested.
作者报告了6例在恶性疾病过程中发生手指坏死的新病例。没有一位患者患有任何其他可解释手指坏死的疾病。他们讨论了这两种情况之间关系的机制:血液高粘滞性、血小板增多症、红细胞增多症、冷球蛋白以及免疫复合物的产生。文中提到了博来霉素的特殊作用。有人提出存在真正副肿瘤综合征的可能性。