DNA与碳水化合物的相互作用。单糖和二糖对小牛胸腺DNA溶液结构的影响。
DNA-carbohydrate interaction. The effects of mono- and disaccharides on the solution structure of calf-thymus DNA.
作者信息
Tajmir-Riahi H A, Naoui M, Diamantoglou S
机构信息
Centre de Recherche en Photobiophysique, Université du Québec à Trois-Riviéres, Canada.
出版信息
J Biomol Struct Dyn. 1994 Aug;12(1):217-34. doi: 10.1080/07391102.1994.10508098.
We report the interaction of calf-thymus DNA with D-glucose, D-fructose, D-galactose and sucrose in aqueous solution at physiological pH with sugar/DNA(P)(P = phosphate) molar ratios (r) of 1/10, 1/5, 1, 5 and 10. FTIR difference spectroscopy was used to characterize the nature of sugar-DNA interaction and correlations between spectral changes and structural variations for both sugar and DNA complexes have been established.
我们报告了在生理pH值的水溶液中，小牛胸腺DNA与D-葡萄糖、D-果糖、D-半乳糖和蔗糖的相互作用，糖/DNA（P）（P = 磷酸）摩尔比（r）分别为1/10、1/5、1、5和10。利用傅里叶变换红外差示光谱法表征了糖与DNA相互作用的性质，并建立了糖和DNA复合物光谱变化与结构变化之间的相关性。
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