Kato M, Hattori T, Takahashi M, Yanagita N, Nakashima I
Department of Otorhinolaryngology, Nagoya University School of Medicine, Japan.
Br J Clin Pract. 1994 Nov-Dec;48(6):299-301.
In this study, prophylactic treatment with ketotifen and examination of subjective symptoms, blood eosinophil count and serum eosinophil cationic protein (ECP) values were carried out from the pre- to postpollinosis season to evaluate the effects of ECP and characterise the effects of prophylactic treatment on the appearance of these mediators in relation to clinical symptoms. We found that: serum ECP values during the season and post-season were significantly higher than those during the pre-season; there was a significant correlation between serum ECP value and blood eosinophil count during the season; and the levels for all three of the above parameters in the prophylactic treatment group were significantly lower than those in the no-treatment group during the season.
