Bertorini T, Halford H, Lawrence J, Vo D, Wassef M
Department of Neurology, University of Tennessee, Memphis 38163.
J Neuroimaging. 1995 Jan;5(1):9-15. doi: 10.1111/jon1995519.
The diagnosis of acute Guillain-Barré syndrome and chronic inflammatory demyelinating polyradiculoneuropathy is based on clinical characteristics, abnormalities on nerve conduction studies, and nerve biopsy specimens indicating demyelination. Inflammation and edema are also common findings in nerve specimens. Immunotherapy is helpful in these dysimmune conditions. Occasionally the diagnosis is difficult to make, particularly when electrophysiological testing or nerve biopsy findings are not characteristic. The authors found contrast enhancement of lumbosacral roots in patients with chronic inflammatory demyelinating polyradiculoneuropathy and Guillain-Barré syndrome, but not in those with other demyelinating neuropathies. Contrast-enhanced magnetic resonance imaging could be a useful tool in the diagnosis of the dysimmune inflammatory neuropathies.
急性吉兰-巴雷综合征和慢性炎症性脱髓鞘性多发性神经根神经病的诊断基于临床特征、神经传导研究异常以及显示脱髓鞘的神经活检标本。炎症和水肿也是神经标本中的常见发现。免疫疗法对这些免疫性疾病有帮助。偶尔诊断会很困难，尤其是当电生理测试或神经活检结果不典型时。作者发现慢性炎症性脱髓鞘性多发性神经根神经病和吉兰-巴雷综合征患者的腰骶神经根有对比增强，但其他脱髓鞘性神经病患者则没有。对比增强磁共振成像可能是诊断免疫性炎症性神经病的有用工具。
