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通过持续输注促黄体激素释放激素1诱导促黄体激素高峰。

Induction of LH surges by continuous infusion of LH-RH1.

作者信息

Schuiling G A, De Koning J, Zürcher A F, Gnodde H P, Van Rees G P

出版信息

Neuroendocrinology. 1976;20(2):151-6. doi: 10.1159/000122478.

DOI:10.1159/000122478
PMID:785294
Abstract

Preovulatory LH surges were measured in cannulated proestrous rats. Such LH peaks were also obtained by infusing pentobarbital-blocked animals with LH-RH for periods of up to 20 h; this suggested that the pituitary LH stores were exhausted. However, the total amount of LH secreted appeared more or less determined by the LH-RH dose, indicating that the size of the releasable LH pool is not fixed.

摘要

在插管的动情前期大鼠中测量排卵前促黄体生成素(LH)高峰。通过向戊巴比妥阻断的动物注射LH-RH长达20小时,也能获得这样的LH峰值;这表明垂体LH储备已耗尽。然而,分泌的LH总量似乎或多或少由LH-RH剂量决定,这表明可释放的LH池大小并非固定不变。

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引用本文的文献

1
Studies on the modulation of the desensitization of the pituitary gland by luteinizing hormone-releasing hormone in the ovariectomized rat.关于促黄体生成素释放激素对去卵巢大鼠垂体脱敏作用调节的研究。
Experientia. 1986 Mar 15;42(3):304-7. doi: 10.1007/BF01942515.
2
Comparison of the time courses of luteinizing hormone (LH) secretion rates during continuous stimulation by LH-releasing hormone (LH-RH) in vivo and in vitro.体内和体外促黄体生成激素释放激素(LH-RH)持续刺激过程中促黄体生成素(LH)分泌率的时间进程比较。
Experientia. 1986 Jan 15;42(1):60-2. doi: 10.1007/BF01975896.