Kauffman W M, Fletcher B D, Hanna S L, Meyer W H
St. Jude Children's Research Hospital, Department of Diagnostic Imaging, Memphis, TN 38101.
Magn Reson Imaging. 1994;12(8):1147-53. doi: 10.1016/0730-725x(94)90079-7.
The objective of this study was to determine the value of magnetic resonance (MR) imaging in diagnosing local recurrence of Ewing sarcoma. We retrospectively reviewed radiographs, Tc99m-methylene diphosphonate (MDP) skeletal scintigraphy, computed tomography scans, and MR studies of 11 patients who had local recurrences of osseous Ewing sarcoma following initial responses to chemotherapy and local radiation. The MR images were compared to those of a control group of nine patients who had no evidence of relapse. T1- and T2-weighted MR images identified 9 of the 11 recurrences. Computed tomography was diagnostic in 4 of 6 cases evaluated, Tc99m-MDP bone scintigraphy in 4 of 11 cases, and plain radiographs in 2 of 10. MR findings at relapse included changes in signal intensity, increased extent of abnormal marrow signal on T1- and T2-weighted images, and identification of a new soft tissue mass. These findings suggest that MR imaging is valuable in the routine follow-up of primary osseous Ewing sarcoma.
本研究的目的是确定磁共振（MR）成像在诊断尤因肉瘤局部复发中的价值。我们回顾性分析了11例骨肉瘤型尤因肉瘤患者的X线片、锝99m-亚甲基二膦酸盐（MDP）骨闪烁显像、计算机断层扫描（CT）及MR检查结果，这些患者在初始化疗和局部放疗后出现了骨肉瘤型尤因肉瘤的局部复发。将这些MR图像与9例无复发证据的对照组患者的图像进行了比较。T1加权和T2加权MR图像识别出了11例复发中的9例。在评估的6例病例中，CT诊断出4例，锝99m-MDP骨闪烁显像在11例中诊断出4例，X线平片在10例中诊断出2例。复发时的MR表现包括信号强度改变、T1加权和T2加权图像上异常骨髓信号范围增加以及发现新的软组织肿块。这些结果表明，MR成像在原发性骨肉瘤型尤因肉瘤的常规随访中具有重要价值。
