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[脊髓肿瘤患者脑脊液的过氧化物化学发光]

[Peroxide chemiluminescence of the cerebrospinal fluid in spinal cord tumors].

作者信息

Okladnikov G I, Kamenskaia V V, Belykh V B, Okladnikova N G, Kurov O M

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 1994;94(4):30-3.

PMID:7856372
Abstract

Spontaneous and initiated by hydrogen peroxide chemiluminescence was evaluated before and after freezing of the CSF from 20 patients with various spinal tumors and 10 controls with intervertebral lumbar osteochondrosis. The intensity of the above chemiluminescence was found significantly different in tumors and osteochondrosis. Cryotreatment induced marked changes in CSF chemiluminescence, especially in extramedullary spinal tumors. CSF treatment with hydrogen peroxide entailed alterations in free radical oxidation which can serve an additional criterion in combined diagnosis of spinal cord tumors.

摘要

对20例患有各种脊柱肿瘤的患者及10例患有腰椎骨软骨病的对照者的脑脊液在冷冻前后的自发及由过氧化氢引发的化学发光进行了评估。发现上述化学发光强度在肿瘤患者和骨软骨病患者中存在显著差异。冷冻处理引起了脑脊液化学发光的显著变化,尤其是髓外脊柱肿瘤。用过氧化氢处理脑脊液会导致自由基氧化的改变,这可作为脊髓肿瘤联合诊断的一项附加标准。

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