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[患有脑肿瘤和脊髓压迫症犬的脑脊液细胞学检查。第4部分]

[Cytology of the cerebrospinal fluid in dogs with brain tumors and spinal cord compression. Part 4].

作者信息

Grevel V, Machus B, Steeb C

机构信息

Klinik und Poliklinik für kleine Haustiere, Freien Universität Berlin.

出版信息

Tierarztl Prax. 1992 Aug;20(4):419-28.

PMID:1412436
Abstract

The results of cerebrospinal fluid (CSF) cytology of 9 dogs with brain tumors and 50 dogs with spinal cord compression are discussed. Of the 50 dogs with spinal cord compression, disc protrusion was diagnosed in 31, myelomalacia in 7, discospondylitis in 3 and spinal cord tumors in 9 dogs. In 4 of 9 dogs with brain tumors, tumor cells could be found by the sedimentation apparatus of Kölmel. Pleocytosis existed in 6 patients. In about 70% (29 of 41) of cases with disc protrusion, more than 200 cells could be evaluated in the CSF sediment, consisting mostly of transformed lymphocytes and activated monocytes. As the neurologic deficits increased, the amount of cells and especially cell complexes increased. This was especially evident in cases with myelomalacia of the spinal cord. Only in cases with discospondylitis or spinal cord neoplasia was the CSF cytology unchanged.

摘要

本文讨论了9只患有脑肿瘤的犬和50只患有脊髓压迫症的犬的脑脊液(CSF)细胞学检查结果。在50只患有脊髓压迫症的犬中,31只被诊断为椎间盘突出,7只患有脊髓软化症,3只患有椎间盘脊椎炎,9只患有脊髓肿瘤。在9只患有脑肿瘤的犬中,有4只通过Kölmel沉降装置可发现肿瘤细胞。6例患者存在细胞增多。在约70%(41例中的29例)的椎间盘突出病例中,脑脊液沉淀物中可评估出200多个细胞,主要由转化淋巴细胞和活化单核细胞组成。随着神经功能缺损的增加,细胞数量尤其是细胞复合体数量增加。这在脊髓软化症病例中尤为明显。只有在椎间盘脊椎炎或脊髓肿瘤病例中,脑脊液细胞学检查结果才无变化。

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