Machet M C, Stephanov E, de Muret A, Haillot O, Fetissof F
Service d'Anatomie Pathologique, Hôpital Trousseau, Tours.
Ann Pathol. 1994;14(6):410-4.
We report a case of primary renal carcinoid tumor associated with kidney malformation. The carcinoid tumor contained cells which stained with anti-chromogranin, anti-serotonin and anti-somatostatin antibodies. The carcinoid tumor was developed on a cystic malformation with transitional epithelium. Immunohistochemical studies revealed positive chromogranin and serotonin cells within the epithelium. The 21 other cases of primary renal carcinoid were reviewed with a particular emphasis on the 2 other cases associated with renal lesions containing endocrine cells. These 3 cases could help to explain the development of primary renal carcinoid tumor.
我们报告一例与肾脏畸形相关的原发性肾类癌肿瘤病例。该类癌肿瘤包含可被抗嗜铬粒蛋白、抗血清素和抗生长抑素抗体染色的细胞。该类癌肿瘤发生于伴有移行上皮的囊性畸形上。免疫组织化学研究显示上皮内嗜铬粒蛋白和血清素细胞呈阳性。回顾了另外21例原发性肾类癌病例,特别关注另外2例与含有内分泌细胞的肾脏病变相关的病例。这3例病例有助于解释原发性肾类癌肿瘤的发生。