Costa F V
Istituto di Clinica Medica III, Università degli Studi di Bologna.
Ann Ital Med Int. 1994 Oct;9 Suppl:50S-53S.
During the last 20 years antihypertensive treatment has given excellent results in terms of prevention of cardiovascular complications. However these results, for some reasons, are less satisfactory than those theoretically possible. The problems we need to solve are many and all contribute to reduce the efficacy of therapy. First of all it is necessary to make a correct diagnosis of hypertension to avoid treating normotensive subjects. The use of continuous ambulatory blood pressure monitoring in some cases can be useful to clarify these situations and also to better evaluate the efficacy of therapeutic regimens. In the vast majority of cases, however, the traditional blood pressure recordings, if correctly performed, can give satisfactory and sufficient information. After a correct diagnosis is made the physician must start with the patient an open-minded cooperation based on confidence. He must clearly explain the goals and the methods of therapy and encourage, instead of frighten, the patient. The next step is the choice of the kind of treatment in which many factors must be kept in mind and in which the physician must have a deep knowledge of the patient and of the drugs. Treatment has a high probability rate of a good patient's compliance only if it does not cause adverse reactions and if the therapeutic scheme is simple. Studies on compliance have shown that it is possible to identify those patients at risk of low compliance even before the beginning of therapy and it has been shown that adverse reactions especially if the patient has not been informed by the doctor, can cause a dramatic fall in compliance.(ABSTRACT TRUNCATED AT 250 WORDS)
在过去20年里,抗高血压治疗在预防心血管并发症方面取得了优异成果。然而,由于某些原因,这些成果不如理论上可能达到的那么令人满意。我们需要解决的问题众多,且都导致治疗效果降低。首先,必须正确诊断高血压,以免对血压正常的患者进行治疗。在某些情况下,使用动态血压监测有助于澄清这些情况,也能更好地评估治疗方案的疗效。然而,在绝大多数情况下,如果操作正确,传统的血压测量也能提供令人满意且足够的信息。做出正确诊断后,医生必须与患者展开基于信任的坦诚合作。他必须清楚地解释治疗目标和方法,鼓励而非吓唬患者。下一步是选择治疗方式,此时必须考虑诸多因素,医生必须深入了解患者和药物。只有治疗不引起不良反应且治疗方案简单,患者才极有可能很好地配合治疗。关于治疗依从性的研究表明,甚至在治疗开始前就能识别出那些依从性低的风险患者,而且已经表明,不良反应,尤其是如果医生未告知患者,会导致依从性大幅下降。(摘要截选于250词)