[3',4'-二丙酰基瑞士乳杆菌素的临床药理有效数据]
[Clinical-pharmacological effective data on 3',4',-dipropionylhelveticosol].
作者信息
Sziegoleit W, Förster W, Maier E, Assmann I, Fiehring H, Schulz H E, Crodel H W, Gutschker A
出版信息
Z Gesamte Inn Med. 1976 Jul 1;31(13):501-3.
PMID:785835
Abstract
In experiments of treatment carried out on 39 patients with cardiac insufficiency with tachyarrhythmia for the partially synthetic, new heart glycoside 3',4'-dipropionyl helveticosol the following clinico-pharmacological data of efficacy were approximately established on an average: level of full efficacy 2.7 mg, daily coefficient of disappearing 40%, coefficient of enteral absorption 30%, daily maintenance dose intravenously 1.1 mg and orally 3.7 mg.
摘要
在对39例伴有快速性心律失常的心功能不全患者进行的治疗实验中，对于部分合成的新型强心苷3',4'-二丙酰羟基毛地黄毒苷，大致平均确定了以下疗效的临床药理学数据：完全疗效水平为2.7毫克，每日消除系数为40%，肠道吸收系数为30%，静脉注射每日维持剂量为1.1毫克，口服为3.7毫克。
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