Bondil P
Service d'Urologie-Andrologie, CHD de Chambéry.
Prog Urol. 1994 Oct;4(5 Suppl 2):84-8.
Prolonged pharmacological erection (PPE) is a blocked erection lasting for more than 4 hours after intracavernosal injection (ICI) of an erectogenic drug. This form of priapism is the commonest complication of ICI in the diagnosis and treatment of impotence. It carries a potential risk of acute ischaemia of the corpora cavernosa with subsequent destruction of the erectile tissues. Any blocked erection must therefore be treated within 4 hours. Medical treatment is sufficient in the very great majority of cases, provided it is performed early. The indication for each medical method (simple measures, oral or, more especially, intracavernosal alpha-stimulant treatment, decompressive cavernosal puncture) depends on the duration of PPE and/or the presence of signs of tissue ischaemia (pain). Surgery is only indicated in the rare cases of failure of medical treatment. PPE can now be prevented by means of selection and information of patients and the recent introduction of less dangerous drugs.
药物性持续性勃起（PPE）是指在海绵体内注射勃起药物后，勃起持续超过4小时。这种阴茎异常勃起形式是阴茎海绵体内注射治疗阳痿时最常见的并发症。它存在海绵体急性缺血的潜在风险，随后会导致勃起组织受损。因此，任何持续性勃起都必须在4小时内进行治疗。如果能早期进行，绝大多数情况下药物治疗就足够了。每种药物治疗方法（简单措施、口服或更特别的海绵体内α-激动剂治疗、减压性海绵体穿刺）的适应证取决于PPE的持续时间和/或组织缺血体征（疼痛）的存在情况。仅在药物治疗罕见的失败病例中才考虑手术治疗。现在可以通过患者选择、告知患者以及最近引入危险性较小的药物来预防PPE。
