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[大连地区不同人群军团菌感染的对比研究]

[Comparative study on Legionella infection in different groups of population in Dalian area].

作者信息

Wang Y, Lei Z, Ju C

机构信息

First Affiliated Hospital of Dalian Medical University.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 1994 Oct;15(5):271-4.

PMID:7859259
Abstract

Using a microagglutination test, the prevalence of antibodies against three species (10 groups) of Legionella was determined in 300 healthy donors, 120 non-pneumonic patients with immunodeficiency and 158 patients with pneumonia. The results showed that there were significant differences among all groups on positive rate and GMT in three groups. Lp6 was the highest, Lp1 and Lp8 came second. There were significant differences among three groups in positive rate and GMT to Lp1, Lp2, Lp6 and Lp8, in the group of patients with pneumonia was highest, the group of non-pneumonic patients with immunodeficiency was second and healthy group was the lowest. It was suggested that the infection with Lp6, Lp1, Lp8 was predominant in population in Dalian area. The latent infection, subclinical infection and legionella pneumonia in population might be existence simultaneously. Using test-tube agglutination, the paired sera collected from 74 pneumonic patients were studied, it was showed that 5.4% of admitted pneumonic patients was legionellosis.

摘要

采用微量凝集试验,测定了300名健康献血者、120名非肺炎免疫缺陷患者和158名肺炎患者中针对三种军团菌(10个血清型)抗体的流行情况。结果显示,三组在阳性率和几何平均滴度(GMT)上均存在显著差异。Lp6最高,Lp1和Lp8次之。三组在针对Lp1、Lp2、Lp6和Lp8的阳性率和GMT方面存在显著差异,肺炎患者组最高,非肺炎免疫缺陷患者组次之,健康组最低。提示大连地区人群中Lp6、Lp1、Lp8感染较为普遍。人群中可能同时存在潜伏感染、亚临床感染和军团菌肺炎。采用试管凝集试验,对74例肺炎患者采集的配对血清进行研究,结果显示5.4%的入院肺炎患者为军团菌病。

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