Lloyd D J, Reid T M
Acta Paediatr Scand. 1976 Sep;65(5):585-91. doi: 10.1111/j.1651-2227.1976.tb04936.x.
Recent reports indicate that the group B haemolytic streptococcus has now assumed a major role in neonatal septicaemia in the United Kingdom. Of particular concern are the absence of premonitory signs, the fulminating nature of the infection and the high mortality. 31 cases from which this organism was isolated during the first week of life included 5 cases of neonatal septicaemia, 4 of which proved fatal. An attempt was made (a) to identify the group of neonates at greatest risk and (b) to formulate guidelines for early detection and treatment. Study indicates the importance of apnoea as a sign of infection particularly in those infants who are preterm, of low birth weight and asphyxiated. There is need for aggressive bacteriological screening and early administration of antibiotics to prevent the high mortality from group B streptococcal infection.
最近的报告表明，B 族溶血性链球菌目前在英国新生儿败血症中扮演着主要角色。特别令人担忧的是缺乏先兆症状、感染的暴发性本质以及高死亡率。在出生第一周内分离出该病原体的 31 例病例中，包括 5 例新生儿败血症，其中 4 例死亡。研究人员试图：（a）确定风险最高的新生儿群体；（b）制定早期检测和治疗指南。研究表明，呼吸暂停作为感染迹象的重要性，特别是在那些早产、低体重和窒息的婴儿中。有必要进行积极的细菌学筛查并尽早使用抗生素，以防止 B 族链球菌感染导致的高死亡率。
