长时间使用止血带对血清碳酸氢盐的影响。

The effect of prolonged tourniquet application on serum bicarbonate.

作者信息

Bany-Mohammed F M, Macknin M L, van Lente F, Medendorp S V

机构信息

Department of Pediatric, Cleveland Clinic Foundation, OH 44195.

出版信息

Cleve Clin J Med. 1995 Jan-Feb;62(1):68-70. doi: 10.3949/ccjm.62.1.68.

DOI:10.3949/ccjm.62.1.68

PMID:7859405

Abstract

BACKGROUND

Many clinicians believe that prolonged tourniquet application lowers the serum bicarbonate concentration in samples drawn from that limb, but this effect has never been examined prospectively.

OBJECTIVE

To test the effect of prolonged tourniquet application before phlebotomy on serum bicarbonate concentration in healthy adults.

METHODS

We drew blood samples from 27 healthy adult volunteers without a tourniquet and again 1, 3, and 5 minutes after applying a blood pressure cuff and inflating it to the mean arterial pressure.

RESULTS

The mean bicarbonate concentration was 27.3 +/- 2.26 mmol/L (standard deviation) at baseline, 27.7 +/- 2.39 mmol/L at 1 minute, 27.7 +/- 2.05 mmol/L at 3 minutes, and 27.7 +/- 1.96 mmol/L at 5 minutes. The mean change in bicarbonate concentration from baseline was -0.04 +/- 1.02 mmol/L at 1 minute, 0.44 +/- 1.05 mmol/L at 3 minutes, and 0.44 +/- 1.31 mmol/L at 5 minutes. The mean lactate concentration was 1.1 +/- 0.28 mmol/L at baseline, 1.3 +/- 0.65 mmol/L at 1 minute, 1.2 +/- 0.52 mmol/L at 3 minutes, and 1.2 +/- 0.36 mmol/L at 5 minutes. The mean change in lactate concentration from baseline was 0.15 +/- 0.67 mmol/L at 1 minute, 0.11 +/- 0.11 mmol/L at 3 minutes, and 0.12 +/- 0.37 mmol/L at 5 minutes.

CONCLUSIONS

Prolonged tourniquet application before phlebotomy does not lower the serum bicarbonate concentration in healthy adults.

摘要

背景

许多临床医生认为，长时间使用止血带会降低从该肢体采集的样本中的血清碳酸氢盐浓度，但这种影响从未经过前瞻性研究。

目的

测试在静脉穿刺前长时间使用止血带对健康成年人血清碳酸氢盐浓度的影响。

方法

我们从27名健康成年志愿者身上采集血样，一次在未使用止血带时采集，另一次在使用血压袖带并将其充气至平均动脉压后1分钟、3分钟和5分钟分别采集。

结果

基线时碳酸氢盐平均浓度为27.3±2.26 mmol/L（标准差），1分钟时为27.7±2.39 mmol/L，3分钟时为27.7±2.05 mmol/L，5分钟时为27.7±1.96 mmol/L。与基线相比，碳酸氢盐浓度在1分钟时平均变化为-0.04±1.02 mmol/L，3分钟时为0.44±1.05 mmol/L，5分钟时为0.44±1.31 mmol/L。乳酸平均浓度在基线时为1.1±0.28 mmol/L，1分钟时为1.3±0.65 mmol/L，3分钟时为1.2±0.52 mmol/L，5分钟时为1.2±0.36 mmol/L。与基线相比，乳酸浓度在1分钟时平均变化为0.15±0.67 mmol/L，3分钟时为0.11±0.11 mmol/L，5分钟时为0.12±0.37 mmol/L。