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立陶宛农村人口的遗传多样性:以ABO和Rh(D)血型的变异为例

Genetic diversity in the Lithuanian rural population as illustrated by variation in the ABO and Rh(D) blood groups.

作者信息

Kucinskas V, Radikas J, Rasmuson M

机构信息

Human Genetics Center, Vilnius University, Lithuania.

出版信息

Hum Hered. 1994 Nov-Dec;44(6):344-9. doi: 10.1159/000154242.

DOI:10.1159/000154242
PMID:7860088
Abstract

Regional and temporal variations in the ABO and Rh blood group gene frequencies were studied in the rural population of Lithuania. The total material, comprising blood group data for about 37,000 individuals, was subdivided according to place of residence into 401 parishes, 44 administrative districts and 6 ethnolinguistic regions. A significant regional heterogeneity was found. Gene diversity figures were higher than those observed in some other countries when studied at similar hierarchical levels. The gene frequency variation at the district level was compared to expected effects of genetic drift and migration and it was estimated that a migration rate of 5-10% would counter genetic drift in the rural population of Lithuania.

摘要

对立陶宛农村人口的ABO和Rh血型基因频率的区域和时间变化进行了研究。总共约37000人的血型数据资料,根据居住地细分为401个教区、44个行政区和6个民族语言区。发现了显著的区域异质性。在类似层次水平上进行研究时,基因多样性数据高于在其他一些国家观察到的数据。将地区层面的基因频率变化与遗传漂变和迁移的预期影响进行了比较,估计5%-10%的迁移率将抵消立陶宛农村人口中的遗传漂变。

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