来自枯草芽孢杆菌的芽孢形成蛋白SpoIVFB在没有其他芽孢形成基因产物的情况下可增强σ因子前体Pro-σK的加工。
Sporulation protein SpoIVFB from Bacillus subtilis enhances processing of the sigma factor precursor Pro-sigma K in the absence of other sporulation gene products.
作者信息
Lu S, Cutting S, Kroos L
机构信息
Department of Biochemistry, Michigan State University, East Lansing 48824.
出版信息
J Bacteriol. 1995 Feb;177(4):1082-5. doi: 10.1128/jb.177.4.1082-1085.1995.
Abstract
Processing of inactive pro-sigma K to active sigma K in the mother cell compartment of sporulating Bacillus subtilis is governed by a signal transduction pathway emanating from the forespore and involving SpoIVFB in the mother cell. Coexpression of spoIVFB and sigK (encoding pro-sigma K) genes in growing B. subtilis or Escherichia coli enhanced pro-sigma K processing in the absence of other sporulation-specific gene products. The simplest explanation of these results is that SpoIVFB is a protease that processes pro-sigma K.
摘要
在枯草芽孢杆菌芽孢形成过程中，母细胞区室中无活性的前σK加工成活性σK是由从前芽孢发出并涉及母细胞中SpoIVFB的信号转导途径控制的。在生长的枯草芽孢杆菌或大肠杆菌中共表达spoIVFB和sigK（编码前σK）基因，在没有其他芽孢形成特异性基因产物的情况下增强了前σK的加工。对这些结果最简单的解释是SpoIVFB是一种加工前σK的蛋白酶。
相似文献
1
Sporulation protein SpoIVFB from Bacillus subtilis enhances processing of the sigma factor precursor Pro-sigma K in the absence of other sporulation gene products.
J Bacteriol. 1995 Feb;177(4):1082-5. doi: 10.1128/jb.177.4.1082-1085.1995.
2
Sporulation operon spoIVF and the characterization of mutations that uncouple mother-cell from forespore gene expression in Bacillus subtilis.
J Mol Biol. 1991 Oct 20;221(4):1237-56. doi: 10.1016/0022-2836(91)90931-u.
3
BofA protein inhibits intramembrane proteolysis of pro-sigmaK in an intercompartmental signaling pathway during Bacillus subtilis sporulation.
Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6385-90. doi: 10.1073/pnas.0307709101. Epub 2004 Apr 15.
4
SpoIVB and CtpB are both forespore signals in the activation of the sporulation transcription factor sigmaK in Bacillus subtilis.
J Bacteriol. 2007 Aug;189(16):6021-7. doi: 10.1128/JB.00399-07. Epub 2007 Jun 8.
5
Membrane topology of the Bacillus subtilis pro-sigma(K) processing complex.
J Bacteriol. 2000 Jan;182(2):278-85. doi: 10.1128/JB.182.2.278-285.2000.
6
Evidence that SpoIVFB is a novel type of membrane metalloprotease governing intercompartmental communication during Bacillus subtilis sporulation.
J Bacteriol. 2000 Jun;182(11):3305-9. doi: 10.1128/JB.182.11.3305-3309.2000.
7
Channels modestly impact compartment-specific ATP levels during Bacillus subtilis sporulation and a rise in the mother cell ATP level is not necessary for Pro-σ cleavage.
Mol Microbiol. 2020 Oct;114(4):563-581. doi: 10.1111/mmi.14560. Epub 2020 Jun 29.
8
Subcellular localization of proteins governing the proteolytic activation of a developmental transcription factor in Bacillus subtilis.
Genes Cells. 1996 Jun;1(6):529-42. doi: 10.1046/j.1365-2443.1996.d01-262.x.
9
Characterization of bofA, a gene involved in intercompartmental regulation of pro-sigma K processing during sporulation in Bacillus subtilis.
J Bacteriol. 1992 May;174(10):3177-84. doi: 10.1128/jb.174.10.3177-3184.1992.
10
Processing of the mother-cell sigma factor, sigma K, may depend on events occurring in the forespore during Bacillus subtilis development.
Proc Natl Acad Sci U S A. 1990 Dec;87(24):9722-6. doi: 10.1073/pnas.87.24.9722.
引用本文的文献
1
Substrate engagement by the intramembrane metalloprotease SpoIVFB.
Nat Commun. 2024 Oct 17;15(1):8276. doi: 10.1038/s41467-024-52634-6.
2
Conserved Proline Residues of Bacillus subtilis Intramembrane Metalloprotease SpoIVFB Are Important for Substrate Interaction and Cleavage.
J Bacteriol. 2022 Mar 15;204(3):e0038621. doi: 10.1128/JB.00386-21. Epub 2022 Jan 10.
3
The ins and outs of Bacillus proteases: activities, functions and commercial significance.
FEMS Microbiol Rev. 2022 Jan 18;46(1). doi: 10.1093/femsre/fuab046.
4
Sporulation and Germination in Clostridial Pathogens.
Microbiol Spectr. 2019 Nov;7(6). doi: 10.1128/microbiolspec.GPP3-0017-2018.
5
Diverse mechanisms regulate sporulation sigma factor activity in the Firmicutes.
Curr Opin Microbiol. 2015 Apr;24:88-95. doi: 10.1016/j.mib.2015.01.006. Epub 2015 Feb 1.
6
The Clostridium sporulation programs: diversity and preservation of endospore differentiation.
Microbiol Mol Biol Rev. 2015 Mar;79(1):19-37. doi: 10.1128/MMBR.00025-14.
7
Spore formation in Bacillus subtilis.
Environ Microbiol Rep. 2014 Jun;6(3):212-25. doi: 10.1111/1758-2229.12130. Epub 2013 Dec 17.
8
Regulated proteolysis in bacterial development.
FEMS Microbiol Rev. 2014 May;38(3):493-522. doi: 10.1111/1574-6976.12050. Epub 2013 Dec 19.
9
Features of Pro-σK important for cleavage by SpoIVFB, an intramembrane metalloprotease.
J Bacteriol. 2013 Jun;195(12):2793-806. doi: 10.1128/JB.00229-13. Epub 2013 Apr 12.
10
Inducible Clostridium perfringens bacteriophages ΦS9 and ΦS63: Different genome structures and a fully functional sigK intervening element.
Bacteriophage. 2012 Apr 1;2(2):89-97. doi: 10.4161/bact.21363.
本文引用的文献
1
Bacillus subtilis sporulation: regulation of gene expression and control of morphogenesis.
Microbiol Rev. 1993 Mar;57(1):1-33. doi: 10.1128/mr.57.1.1-33.1993.
2
Multilevel regulation of the sporulation transcription factor sigma K in Bacillus subtilis.
J Bacteriol. 1993 Nov;175(22):7341-7. doi: 10.1128/jb.175.22.7341-7347.1993.
3
Overproducing the Bacillus subtilis mother cell sigma factor precursor, Pro-sigma K, uncouples sigma K-dependent gene expression from dependence on intercompartmental communication.
J Bacteriol. 1994 Jul;176(13):3936-43. doi: 10.1128/jb.176.13.3936-3943.1994.
4
Sporulation regulatory protein SpoIIID from Bacillus subtilis activates and represses transcription by both mother-cell-specific forms of RNA polymerase.
J Mol Biol. 1994 Oct 28;243(3):425-36. doi: 10.1006/jmbi.1994.1670.
5
Regulation of the transcription of a cluster of Bacillus subtilis spore coat genes.
J Mol Biol. 1994 Jul 29;240(5):405-15. doi: 10.1006/jmbi.1994.1456.
6
A developmental gene product of Bacillus subtilis homologous to the sigma factor of Escherichia coli.
Nature. 1984;312(5992):376-8. doi: 10.1038/312376a0.
7
Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes.
Anal Biochem. 1980 Nov 15;109(1):76-86. doi: 10.1016/0003-2697(80)90013-5.
8
Construction of a cloning site near one end of Tn917 into which foreign DNA may be inserted without affecting transposition in Bacillus subtilis or expression of the transposon-borne erm gene.
Plasmid. 1984 Jul;12(1):1-9. doi: 10.1016/0147-619x(84)90061-1.
9
Fate of transforming DNA following uptake by competent Bacillus subtilis. I. Formation and properties of the donor-recipient complex.
J Mol Biol. 1971 Mar 14;56(2):209-21. doi: 10.1016/0022-2836(71)90460-8.
10
Processing of a sporulation sigma factor in Bacillus subtilis: how morphological structure could control gene expression.
Cell. 1988 Mar 11;52(5):697-704. doi: 10.1016/0092-8674(88)90407-2.
Zotero 插件