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[电子束计算机断层扫描的动态心血管研究]

[Dynamic cardiovascular studies with electron beam computed tomography].

作者信息

Mousseaux E, Hernigou A, Auguste M, Gaux J C

机构信息

Services de Radiologie de l'Hôpital Broussais, INSERM Unité 66, Paris.

出版信息

J Radiol. 1994 Dec;75(12):669-74.

PMID:7861355
Abstract

Electron Beam CT (EBCT) is still emerging as a new functional imaging procedure in providing high morphological studies and dynamic quantitative functional data. Morphological EBCT studies have previously proven their usefulness in pathologic conditions of the thoracic aorta, in congenital diseases, in cardiac masses or tumors... Functional studies achieved using cine mode and/or flow mode are used to assess both mobility and perfusion of structures. Such dynamic analysis have confirmed that their applications will have a major impact on the knowledge of cardiac physiology, the understanding of cardiovascular diseases, if not in daily patient care. For instance, in studies on ventricular function, among the imaging modalities in current use, EBCT is probably most accurate for the evaluation of systolic regional or global function. EBCT is a cross-sectional imaging methods which overcome an important limitation shared by most other imaging modalities, namely the superimposition of overlapping cardiac and thoracic structures. Since in the method high spatial, contrast, and temporal resolution tomography displays the myocardial wall itself, an accurate delineating of endocardial and epicardial contours in contiguous levels can be obtained. Further developments in computer-automated analysis from dynamic EBCT studies have to be carried out to gain clinical acceptance and to facilitate the routine.

摘要

电子束CT(EBCT)作为一种新的功能成像方法仍在不断发展,它可提供高质量的形态学研究和动态定量功能数据。此前,EBCT形态学研究已证明其在胸主动脉病理状况、先天性疾病、心脏肿块或肿瘤等方面的应用价值。使用电影模式和/或血流模式进行的功能研究可用于评估结构的活动度和灌注情况。这样的动态分析已证实,其应用将对心脏生理学知识、心血管疾病的理解产生重大影响,即便在日常患者护理中并非如此。例如,在心室功能研究中,在目前使用的成像方式中,EBCT可能是评估收缩期局部或整体功能最准确的方法。EBCT是一种横断面成像方法,它克服了大多数其他成像方式共有的一个重要局限,即心脏和胸部结构重叠造成的叠加问题。由于该方法通过高空间、对比度和时间分辨率的断层扫描显示心肌壁本身,因此可以在连续层面上准确描绘心内膜和心外膜轮廓。为了获得临床认可并便于常规应用,还必须对EBCT动态研究的计算机自动分析进行进一步开发。

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