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从获得性免疫缺陷综合征患者淋巴结中检测发酵支原体DNA。

Detection of Mycoplasma fermentans DNA from lymph nodes of acquired immunodeficiency syndrome patients.

作者信息

Sasaki Y, Honda M, Naitou M, Sasaki T

机构信息

Department of Safety Research on Biologics, National Institute of Health, Japan.

出版信息

Microb Pathog. 1994 Aug;17(2):131-5. doi: 10.1006/mpat.1994.1059.

Abstract

Biopsy samples from seven patients with acquired immunodeficiency syndrome were screened for Mycoplasma fermentans, M. pneumoniae and M. genitalium infection by the polymerase chain reaction. M. fermentans DNA was detected in four patients. Various tissues were evaluated and the mycoplasma were mainly detected from lymph nodes. Moreover, mycoplasma genus-specific DNA was isolated from peripheral blood mononuclear cells of asymptomatic human immunodeficiency virus(HIV)-infected individuals (two of 31 HIV-infected individuals). These data suggest that mycoplasma infection in AIDS patients is not uncommon.

摘要

通过聚合酶链反应对7例获得性免疫缺陷综合征患者的活检样本进行发酵支原体、肺炎支原体和生殖支原体感染筛查。在4例患者中检测到发酵支原体DNA。对各种组织进行了评估,支原体主要在淋巴结中检测到。此外,从无症状人类免疫缺陷病毒(HIV)感染者(31例HIV感染者中的2例)的外周血单个核细胞中分离出支原体属特异性DNA。这些数据表明艾滋病患者中的支原体感染并不罕见。

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