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尼古丁可能缓解帕金森病的症状。

Nicotine may relieve symptoms of Parkinson's disease.

作者信息

Fagerström K O, Pomerleau O, Giordani B, Stelson F

机构信息

Pharmacia Research Laboratories, Helsingborg, Sweden.

出版信息

Psychopharmacology (Berl). 1994 Sep;116(1):117-9. doi: 10.1007/BF02244882.

Abstract

Two elderly patients with Parkinson's disease were treated with nicotine gum and patch. Reliable changes in symptomatology were noted, using a single-subject, placebo-control reversal design. Improvement was associated with active nicotine dosing and involved diminished tremor and disorganized thinking in one patient and diminished bradykinesia and increased energy in the other.

摘要

两名老年帕金森病患者接受了尼古丁口香糖和贴片治疗。采用单受试者、安慰剂对照反转设计,观察到症状有可靠变化。改善与活性尼古丁给药有关,其中一名患者震颤减轻、思维紊乱改善,另一名患者运动迟缓减轻、精力增加。

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