Wasserman B A, Lin W, Tarr R W, Haacke E M, Müller E
Department of Radiology, Case Western Reserve University, Ohio.
Radiology. 1995 Mar;194(3):681-6. doi: 10.1148/radiology.194.3.7862962.
To test two-dimensional cardiac-gated phase-contrast (2DGPC) magnetic resonance (MR) imaging in the evaluation of cerebral arteriovenous malformations (AVMs) and the alterations in flow that accompany embolization therapy.
A 2DGPC sequence was used to measure flow velocity in the feeding vessels and corresponding contralateral vessels (CCVs) of seven patients (six men and one woman, 21-55 years of age; mean, 37 years) with cerebral AVMs and in the vessels of four healthy volunteers (all men; mean age, 22 years).
In the patients, the flow in the feeding vessels exceeded the flow in the CCVs by a margin far greater than the asymmetry in flow in the volunteers. The mean reduction in flow after embolization was 54.9% +/- 11.1 in embolized feeding vessels (n = 6) and 5.3% +/- 2.8 in nonembolized vessels (n = 3). Postembolization flow enhancement was observed in the CCV (n = 2), which suggests a degree of autoregulatory dysfunction.
This technique can be used to evaluate the flow patterns of AVMs and the hemodynamic changes that occur with embolization.
测试二维心脏门控相位对比（2DGPC）磁共振（MR）成像在评估脑动静脉畸形（AVM）以及伴随栓塞治疗的血流变化中的应用。
使用2DGPC序列测量7例脑AVM患者（6例男性，1例女性，年龄21 - 55岁；平均37岁）供血血管及相应对侧血管（CCV）中的血流速度，以及4名健康志愿者（均为男性；平均年龄22岁）血管中的血流速度。
在患者中，供血血管中的血流超过CCV中的血流，其差值远大于志愿者血流的不对称性。栓塞后，栓塞的供血血管（n = 6）血流平均减少54.9% +/- 11.1%，未栓塞血管（n = 3）血流平均减少5.3% +/- 2.8%。在CCV中观察到栓塞后血流增强（n = 2），这提示存在一定程度的自动调节功能障碍。
该技术可用于评估AVM的血流模式以及栓塞后发生的血流动力学变化。
