Delpont E, Martin-Moutot N, Brunetto J L, Desnuelle C
Laboratoire d'Explorations Fonctionnelles du Système Nerveux, CHU de Nice.
Rev Neurol (Paris). 1994;150(3):244-7.
Two cases of Lambert-Eaton syndrome are reported, one associated with a small cell lung carcinoma, the other without any etiology at the time of the study. None of these cases showed significant titers of calcium channel autoantibodies. The heterogeneity of the Lambert-Eaton syndrome and the responsibility of the autoantibodies detected by immunoprecipitation of the voltage-gated calcium channel in the occurrence of the neuromuscular block are discussed.
报告了两例兰伯特-伊顿综合征病例，一例与小细胞肺癌相关，另一例在研究时无任何病因。这些病例均未显示出显著滴度的钙通道自身抗体。讨论了兰伯特-伊顿综合征的异质性以及通过电压门控钙通道免疫沉淀检测到的自身抗体在神经肌肉阻滞发生中的作用。
