[癫痫发作与异环磷酰胺-美司钠治疗]
[Epileptic seizures and treatment with ifosfamide-mesna].
作者信息
Somma-Mauvais H, Farisse P, Viallat J R
机构信息
Service d'Explorations Fonctionnelles du Système Nerveux, CHU, Hôpital Sainte-Marguerite, Marseille.
出版信息
Rev Neurol (Paris). 1994;150(4):307-8.
Generalized and partial seizures with secondary generalization were observed during ifosfamide-mesna (IFO) treatment in a patient with lung epidermoid carcinoma. Seizures appeared in a stereotyped manner on the 3rd of the 4th and 6th day of treatment with IFO. Partially resolutive confusion was observed after the last cure. Brain CTS were normal. The responsibility of IFO is considered in the development of these neurological toxic manifestations.
在一名肺表皮样癌患者接受异环磷酰胺-美司钠（IFO）治疗期间，观察到全身性发作和继发全身性发作的部分性发作。在使用IFO治疗的第4天和第6天的第3天，癫痫发作以刻板的方式出现。最后一次治疗后观察到部分缓解的意识模糊。脑部CT扫描正常。这些神经毒性表现的发生被认为与IFO有关。
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